Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17356160 | 0.89 | CASR (0.38) | CASRNPC1MAPTIDH1 | |
| SCHEMBL15837150 | 0.79 | MAPT (0.39) | NPC1MAPT | |
| SCHEMBL15825233 | 0.76 | NPC1 (0.32) | NPC1MAPT | |
| SCHEMBL15832224 | 0.76 | RXRA (0.37) | NPC1MAPTIDH1 | |
| SCHEMBL17268491 | 0.69 | ALDH1A1 (0.32) | CASRMAPT | |
| SCHEMBL17356153 | 0.69 | AR (0.43) | CASRIDH1 | |
| SCHEMBL19311809 | 0.68 | IDH1 (0.44) | CASRNPC1MAPTIDH1 | |
| SCHEMBL16045131 | 0.68 | IDH1 (0.44) | CASRNPC1MAPTIDH1 | |
| SCHEMBL17356167 | 0.67 | GABRG2 (0.33) | — | |
| SCHEMBL15935047 | 0.67 | CYP11B1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914727-B2 | Factor IXa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-03-13 | — | — | US | disclosed |