Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.70 |
| ▸ | TST | Q16762 | 2/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | USP2 | O75604 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | HAT1 | O14929 | 4/20 | 0.59 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CASP7 | P55210 | 3/20 | 0.59 |
| ▸ | CASP1 | P29466 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201499 | 0.86 | ESR1 (0.77) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL14571231 | 0.84 | ESR1 (0.89) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| Riboflavin 5'-Phosphate SCHEMBL41133 | 0.82 | ESR1 (1.00) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| Riboflavin 5'-Phosphate SCHEMBL190079 | 0.82 | ESR1 (1.00) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| Riboflavin 5'-Phosphate SCHEMBL1532396 | 0.82 | ESR1 (1.00) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| Riboflavin 5'-Phosphate SCHEMBL297863 | 0.82 | ESR1 (1.00) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| Riboflavin 5'-Phosphate SCHEMBL6681480 | 0.81 | ESR1 (0.98) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL18973884 | 0.80 | ESR1 (0.77) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL19424100 | 0.80 | MEN1 (0.74) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL24201806 | 0.80 | MEN1 (0.74) | ESR1NR3C1ADRB2HTR2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11819550-B2 | Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) | EAGLE BIOLOGICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20210038718-A1 | Liquid Protein Formulations Containing Organophosphates | EAGLE BIOLOGICS, INC. | 2021-02-11 | — | — | US | disclosed |
| US-10821184-B2 | Liquid protein formulations containing thiamine pyrophosphate (TPP) | EAGLE BIOLOGICS, INC. (US) | 2020-11-03 | — | — | US | disclosed |
| US-20180153997-A1 | Liquid Protein Formulations Containing Organophosphates | EAGLE BIOLOGICS, INC. | 2018-06-07 | — | — | US | disclosed |
| US-9913905-B2 | Liquid pharmaceutical formulations for injection comprising thiamine pyrophosphate 1-(3-aminopropyl)-2-methyl-1H-imidazole and uses thereof | EAGLE BIOLOGICS, INC. (US) | 2018-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11819550-B2 | Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) | PDE7A, PDE8A, PDE8B | ESR1 4375/4885NR3C1 3668/4885ADRB2 2148/4885 |
| US-10821184-B2 | Liquid protein formulations containing thiamine pyrophosphate (TPP) | PLPBP, ITPA, PLTP | ESR1 4842/4885NR3C1 4609/4885ADRB2 4536/4885 |
| US-20210038718-A1 | Liquid Protein Formulations Containing Organophosphates | IGFBP1, IGFBP5, IGF2BP1 | ESR1 4439/4885NR3C1 3626/4885ADRB2 4494/4885 |
| US-20180153997-A1 | Liquid Protein Formulations Containing Organophosphates | IGFBP1, IGFBP5, IGF2BP1 | ESR1 4439/4885NR3C1 3626/4885ADRB2 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.