Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954637 | 0.83 | ALDH1A1 (0.34) | ALDH1A1NR3C2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18164015 | 0.76 | GAA (0.38) | ALDH1A1SMN1; SMN2NR3C2CHRNB2CHRNB4 | |
| SCHEMBL19954525 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2NR3C2 | |
| SCHEMBL19954591 | 0.70 | MAPK1 (0.35) | NR3C2 | |
| SCHEMBL19954622 | 0.70 | GAA (0.37) | ALDH1A1SMN1; SMN2NR3C2 | |
| SCHEMBL21023768 | 0.69 | POLB (0.33) | NR3C2 | |
| SCHEMBL21023586 | 0.69 | GAA (0.39) | NR3C2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19954580 | 0.68 | BTK (0.36) | — | |
| SCHEMBL19954595 | 0.67 | IL1B (0.35) | NR3C2 | |
| SCHEMBL16805955 | 0.67 | ALOX15 (0.45) | ALDH1A1SMN1; SMN2NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914706-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |