Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19836420 | 0.87 | ACHE (0.46) | XDHSLC22A12ACHE | |
| SCHEMBL15337448 | 0.83 | XDH (0.45) | XDHSLC22A12 | |
| SCHEMBL24680031 | 0.83 | XDH (0.44) | XDHACHE | |
| SCHEMBL17639918 | 0.81 | ALDH1A1 (0.46) | XDHSLC22A12 | |
| SCHEMBL18066881 | 0.81 | XDH (0.43) | XDHSLC22A12 | |
| SCHEMBL15783514 | 0.79 | HTR1A (0.44) | XDHSLC22A12 | |
| SCHEMBL18923534 | 0.79 | AR (0.44) | XDH | |
| SCHEMBL171743 | 0.78 | MAOA (0.46) | — | |
| SCHEMBL13678365 | 0.78 | XDH (0.48) | XDH | |
| SCHEMBL13678298 | 0.78 | AAK1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9913843-B2 | Protein kinase C inhibitors and uses thereof | RIGEL PHARMACEUTICALS, INC. (US) | 2018-03-13 | — | — | US | disclosed |