Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 4/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17321489 | 0.78 | EGLN1 (0.43) | ALKBH1EGLN1PTGS2RAB9AHPGD | |
| SCHEMBL27665788 | 0.78 | HPGDS (0.51) | ALKBH1RAB9ASMN1; SMN2HPGDGAA | |
| SCHEMBL27684819 | 0.73 | HPGDS (0.51) | ALKBH1RAB9ASMN1; SMN2HPGDGAA | |
| SCHEMBL27685236 | 0.73 | LDHA (0.51) | ALKBH1RAB9ASMN1; SMN2HPGDGAA | |
| SCHEMBL2861126 | 0.73 | ALKBH2 (0.63) | ALKBH1EGLN1HPGDSALKBH2 | |
| SCHEMBL17324825 | 0.71 | EGLN1 (0.46) | ALKBH1EGLN1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL17066201 | 0.71 | ALDH1A1 (0.41) | EGLN1PTGS2SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL5319902 | 0.69 | LDHA (0.43) | ALKBH1EGLN1 | |
| SCHEMBL19997283 | 0.69 | EGLN1 (0.44) | ALKBH1EGLN1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL15930139 | 0.69 | NOTUM (0.41) | ALKBH1EGLN1RAB9AHPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269763-A1 | CRTH2 receptor ligands for medicinal uses | 7TM PHARMA A/S (DK) | 2011-11-03 | — | — | US | disclosed |
| US-8022063-B2 | CRTH2 receptor ligands for medicinal uses | 7TM PHARMA A/S (DK) | 2011-09-20 | — | — | US | disclosed |
| EP-2336113-A1 | CRTH2 Receptor Ligands for Medical Use | 7TM Pharma A/S (DK) | 2011-06-22 | — | — | EP | disclosed |
| US-20090099189-A1 | CRTH2 Receptor Ligands For Medicinal Uses | 7TM PHARMA A/S (DK) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099189-A1 | CRTH2 Receptor Ligands For Medicinal Uses | HRH1, HRH2, HRH3 | ALKBH1 3593/4885EGLN1 718/4885EDNRB 1072/4885 |
| US-20110269763-A1 | CRTH2 receptor ligands for medicinal uses | HRH1, HRH2, HRH4 | ALKBH1 3577/4885EGLN1 440/4885EDNRB 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.