Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27684819 | 0.88 | HPGDS (0.51) | HPGDSALKBH2PTGDR2RAB9AMEN1 | |
| SCHEMBL27665788 | 0.88 | HPGDS (0.51) | HPGDSALKBH2PTGDR2RAB9AMEN1 | |
| SCHEMBL27665937 | 0.87 | PTGDR2 (0.52) | LDHAHPGDSALKBH2PTGDR2RAB9A | |
| SCHEMBL5319902 | 0.79 | LDHA (0.43) | LDHAPTGDR2ALKBH1 | |
| SCHEMBL5315020 | 0.78 | LDHA (0.42) | LDHAPTGDR2ALKBH1 | |
| SCHEMBL28761478 | 0.78 | RAB9A (0.51) | HPGDSALKBH2PTGDR2RAB9AMEN1 | |
| SCHEMBL28765396 | 0.76 | RAB9A (0.49) | HPGDSALKBH2PTGDR2RAB9AMEN1 | |
| SCHEMBL1995517 | 0.73 | ALKBH1 (0.41) | HPGDSALKBH2RAB9AMEN1KMT2A | |
| SCHEMBL27685294 | 0.73 | PTGDR2 (0.48) | HPGDSALKBH2PTGDR2RAB9AMEN1 | |
| SCHEMBL17321468 | 0.72 | ALKBH2 (0.68) | HPGDSALKBH2PTGDR2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980664-B | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS | 2011-02-23 | — | — | CN | claimed |
| CN-1980664-A | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS (DK) | 2007-06-13 | — | — | CN | claimed |
| CN-1980664-B | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS | 2011-02-23 | — | — | CN | disclosed |
| CN-1980664-A | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS (DK) | 2007-06-13 | — | — | CN | disclosed |