SCHEMBL19956385

SCHEMBL19956385

COC(O)C1(N(O)C(=O)Cc2c(C)cc(C)cc2Cl)CCN(OC)CC1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.33
S1PR5 Q9H228 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19956403 0.89
SCHEMBL19956379 0.85
SCHEMBL19956381 0.83 SIGMAR1 (0.30)
SCHEMBL12071075 0.82 EPHX2 (0.36) EPHX2
SCHEMBL19956394 0.81 L3MBTL1 (0.32)
SCHEMBL46100 0.79 EPHX2 (0.34) EPHX2S1PR5FFAR4
SCHEMBL19956380 0.78
SCHEMBL46135 0.77 EPHX2 (0.35) EPHX2
SCHEMBL15032112 0.76 L3MBTL1 (0.35) EPHX2
SCHEMBL37359 0.75 OPRM1 (0.35) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2575469-B1 PESTICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-14 EP disclosed