SCHEMBL19956885

SCHEMBL19956885

O=C(CCF)OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
MAPK1 P28482 2/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
TDP1 Q9NUW8 3/20 0.53
KMT2A Q03164 2/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
LMNA P02545 3/20 0.51
HCAR2 Q8TDS4 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
NOTUM Q6P988 1/20 0.48
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
CDC25B P30305 1/20 0.47
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1177836 0.88 ALDH1A1 (0.73) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL13248936 0.86 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL958928 0.86 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL27655876 0.86 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
Hydrochloric Acid SCHEMBL7367924 0.85 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL1364951 0.85 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL246474 0.84 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL3963428 0.84 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL18673 0.84 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL16260122 0.84 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3925944-A1 [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER GRANDIS (BE) 2021-12-22 EP disclosed
EP-3510007-B1 [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER GRANDIS (BE) 2021-07-07 EP disclosed
US-20200405667-A1 [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER GRANDIS (BE) 2020-12-31 US disclosed
EP-3750910-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY VIIV Healthcare UK(No.4) Limited (GB) 2020-12-16 EP disclosed
US-10799470-B2 [18F]-labelled lactate derivative as pet radiotracer GRANDIS (BE) 2020-10-13 US disclosed
US-20190255002-A1 [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER Université Catholique de Louvain (BE) 2019-08-22 US disclosed
EP-3293167-A1 [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER Université Catholique De Louvain (BE) 2018-03-14 EP disclosed
CN-102638984-A Stabilized composition for aqueous suspension agricultural chemical MEIJI SEIKA KAISHA 2012-08-15 CN disclosed
CN-102614013-A Adjustable electrotome smoke suction device for medical operation SHINING WORLD HEALTH CARE CO LTD 2012-08-01 CN disclosed
CN-102307476-A Insecticidal compositions containing N-substituted sulfoximines DOW AGROSCIENCES LLC 2012-01-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190255002-A1 [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER LDHA, LDHB, SLC16A1 ALDH1A1 274/4885MAPK1 2854/4885L3MBTL1 219/4885
US-20200405667-A1 [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER LDHA, LDHB, SLC16A1 ALDH1A1 274/4885MAPK1 2854/4885L3MBTL1 219/4885
US-10799470-B2 [18F]-labelled lactate derivative as pet radiotracer LDHA, LDHB, SLC16A1 ALDH1A1 223/4885MAPK1 3341/4885L3MBTL1 1203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.