Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.46 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.46 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PYGB | P11216 | 1/20 | 0.44 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19961517 | 1.00 | PTPN1 (0.48) | PTPN1GJB2LGALS8LGALS3LGALS4 | |
| SCHEMBL30483914 | 0.87 | PYGB (0.47) | ALDH1A1THRBPYGB | |
| SCHEMBL9235423 | 0.87 | PYGB (0.47) | ALDH1A1THRBPYGB | |
| SCHEMBL20786630 | 0.85 | GLA (0.49) | ALDH1A1THRBPYGBMAPK1 | |
| SCHEMBL24894017 | 0.83 | CA1 (0.54) | LGALS8 | |
| SCHEMBL15704433 | 0.83 | CA1 (0.54) | LGALS8 | |
| SCHEMBL19961988 | 0.82 | LGALS8 (0.45) | PTPN1LGALS8LGALS3LGALS4PYGB | |
| SCHEMBL12616099 | 0.81 | CA1 (0.52) | LGALS8 | |
| SCHEMBL27686935 | 0.81 | ALDH1A1 (0.64) | LGALS8LGALS3LGALS4ALDH1A1THRB | |
| Trehalose SCHEMBL19576005 | 0.80 | MEN1 (0.57) | PTPN1GJB2LGALS8LGALS3LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133705-A1 | TREHALOSE ANALOGUES | CENTRAL MICHIGAN UNIVERSITY | 2023-05-04 | — | — | US | disclosed |
| US-20180072767-A1 | TREHALOSE ANALOGUES | NATIONAL SCIENCE FOUNDATION | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133705-A1 | TREHALOSE ANALOGUES | TREH, TALDO1, GALE | PTPN1 1631/4885GJB2 4028/4885LGALS8 422/4885 |
| US-20180072767-A1 | TREHALOSE ANALOGUES | TREH, TALDO1, GALE | PTPN1 1631/4885GJB2 4028/4885LGALS8 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.