SCHEMBL1995869

SCHEMBL1995869

N=C(N)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.59
EPHX2 P34913 2/20 0.59
IDO1 P14902 2/20 0.56
GAA P10253 2/20 0.55
CA2 P00918 1/20 0.53
CA4 P22748 1/20 0.53
CA5A P35218 1/20 0.53
CA9 Q16790 1/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPT P10636 3/20 0.52
NPC1 O15118 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
SLC6A2 P23975 2/20 0.52
ADRA1A P35348 2/20 0.52
OPRM1 P35372 2/20 0.52
RAB9A P51151 2/20 0.52
KDM4E B2RXH2 1/20 0.52
PKM P14618 1/20 0.52
GLA P06280 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11879263 0.98 EPHX1 (0.57) EPHX1EPHX2IDO1GAACA2
Bicarbonate SCHEMBL7359619 0.93 EPHX1 (0.61) EPHX1EPHX2IDO1GAACA2
Nitric Acid SCHEMBL4490937 0.88 EPHX1 (0.51) EPHX1EPHX2IDO1GAACA2
SCHEMBL891282 0.85 EPHX1 (0.52) EPHX1EPHX2IDO1GAACA2
Hydrochloric Acid SCHEMBL9668292 0.83 EPHX1 (0.50) EPHX1EPHX2IDO1GAACA2
Hydrochloric Acid SCHEMBL11511126 0.82 ALDH1A1 (0.45) EPHX1EPHX2IDO1GAACA2
SCHEMBL30496721 0.82 MAPT (0.57) EPHX1EPHX2IDO1GAACA2
SCHEMBL11879529 0.82 CNR2 (0.43) EPHX1EPHX2IDO1GAACA2
SCHEMBL18286554 0.82 GAA (0.57) GAACA2ALDH1A1MAPTNPC1
SCHEMBL10310181 0.82 MEN1 (0.62) CA2ALDH1A1MAPTNPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120006519-A Ultraviolet aging resistant car cover and preparation method thereof 安徽萨克赛斯纺织科技有限公司 2025-05-16 CN claimed
CN-115957589-B Desulfurization filler and preparation method and application thereof 中国石油化工股份有限公司 2025-01-03 CN claimed
CN-117106451-B Low-damage semiconductor silicon etching solution, preparation method and application thereof 浙江奥首材料科技有限公司 2024-02-20 CN claimed
CN-117106451-A Low-damage semiconductor silicon etching solution, preparation method and application thereof 浙江奥首材料科技有限公司 2023-11-24 CN claimed
CN-115957812-A Modified hollow ceramic fiber and preparation and application thereof 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-115957589-A Desulfurization filler and preparation method and application thereof 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-111019121-A Preparation method of guanidine polymer ionic liquid 石家庄学院 2020-04-17 CN claimed
CN-110804179-A High-molecular ionic liquid with good film forming property and long-term antibacterial activity and application thereof 石家庄学院 2020-02-18 CN claimed
CN-110804198-A Preparation method of antibacterial cellulose degradable composite membrane 石家庄学院 2020-02-18 CN claimed
CN-106380598-B A kind of synthetic method of degradation property and its application 石家庄学院 2018-10-19 CN claimed
EP-1686990-B1 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF US ARMY MED RES MAT COMMAND (US) 2012-09-19 EP claimed
EP-1686990-A4 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF US ARMY MED RES MAT COMMAND (US) 2009-06-03 EP claimed
US-7101902-B2 2-guanidinylimidazolidinedione compounds and methods of making and using thereof THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2006-09-05 US claimed
EP-1686990-A2 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. Army Medical Research and Materiel Command (US) 2006-08-09 EP claimed
WO-2005072082-A2 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) 2005-08-11 WO claimed
US-20050148645-A1 2-Guanidinylimidazolidinedione compounds and methods of making and using thereof ARMY, UNITED STATES 2005-07-07 US claimed
US-3976787-A VASOCONSTRICTION ARMOUR PHARMACEUTICAL COMPANY (US) 1976-08-24 US claimed
US-12595279-B2 Modified nucleoside and synthetic methods thereof Stemirna Therapeutics Co., Ltd. (CN) 2026-04-07 US disclosed
US-3976643-A FROM AN ANILINE AND CYANAMIDE WILLIAM H. RORER, INC. (US) 1976-08-24 US disclosed
US-3976787-A VASOCONSTRICTION ARMOUR PHARMACEUTICAL COMPANY (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050148645-A1 2-Guanidinylimidazolidinedione compounds and methods of making and using thereof GUCY1B2, GUCY1A2, AGK EPHX1 2002/4885EPHX2 1468/4885IDO1 1451/4885
US-12595279-B2 Modified nucleoside and synthetic methods thereof RNMT, NSUN2, RNGTT EPHX1 3996/4885EPHX2 2722/4885IDO1 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.