SCHEMBL1995967

SCHEMBL1995967

CC(C)c1ccc(-c2cc(-c3ccccc3)ccc2OPO)c(C(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
PTGS2 P35354 1/20 0.34
MEN1 O00255 1/20 0.34
APAF1 O14727 1/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
XBP1 P17861 1/20 0.34
PTBP1 P26599 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
GALK1 P51570 1/20 0.34
BLM P54132 1/20 0.34
SMAD3 P84022 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1900765 0.82 S1PR1 (0.34) PTGS2MEN1LMNAMAPTKMT2A
SCHEMBL1996342 0.81 RXRA (0.35) RXRARXRBRXRGMEN1APAF1
SCHEMBL8677464 0.73 LMNA (0.45) RXRARXRBRXRGPTGS2MEN1
SCHEMBL1902946 0.72 RXRA (0.38) RXRARXRBNPC1RAB9AL3MBTL1
SCHEMBL5952575 0.72 S1PR1 (0.33) PTGS2MEN1LMNAMAPTKMT2A
SCHEMBL17810080 0.69 RXRA (0.38) RXRARXRBRXRGPTGS2MEN1
SCHEMBL1902145 0.68 RXRA (0.37) RXRARXRBRXRGPTGS2MEN1
SCHEMBL12806206 0.68 RXRA (0.37) RXRARXRBRXRGPTGS2LMNA
SCHEMBL30103901 0.68 LMNA (0.47) MEN1LMNAMAPTHTTBLM
SCHEMBL22589014 0.68 MEN1 (0.47) RXRARXRBRXRGPTGS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969436-B2 Method of producing a molded article TEIJIN CHEMICALS, LTD. (JP) 2015-03-03 US disclosed
US-20110147992-A1 METHOD OF PRODUCING A MOLDED ARTICLE TEIJIN CHEMICALS, LTD. (JP) 2011-06-23 US disclosed