SCHEMBL1996342

SCHEMBL1996342

CC(C)c1cccc(C(C)C)c1-c1cc(-c2ccccc2)ccc1OPO

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.35
RXRB P28702 2/20 0.35
RXRG P48443 1/20 0.35
SLC6A9 P48067 2/20 0.34
PTPN5 P54829 2/20 0.33
USP1 O94782 1/20 0.33
WDR48 Q8TAF3 1/20 0.33
DHFR P00374 1/20 0.33
MEN1 O00255 1/20 0.33
APAF1 O14727 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
XBP1 P17861 1/20 0.33
PTBP1 P26599 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1995967 0.81 RXRA (0.38) RXRARXRBRXRGSLC6A9PTPN5
SCHEMBL1997761 0.78 IDO1 (0.36) RXRARXRBSLC6A9PTPN5MEN1
SCHEMBL1900765 0.70 S1PR1 (0.34) DHFRMEN1LMNAMAPTKMT2A
SCHEMBL21376221 0.70 DHFR (0.48) DHFRNPC1LMNAMAPTRAB9A
SCHEMBL5952922 0.68 CYP2D6 (0.33) DHFRNPC1LMNAMAPTRAB9A
SCHEMBL1902946 0.68 RXRA (0.38) RXRARXRBSLC6A9NPC1RAB9A
SCHEMBL10598465 0.67 MEN1 (0.47) RXRARXRBRXRGUSP1WDR48
SCHEMBL15833732 0.66 GABRA1 (0.48) PTPN5LMNAMAPTHTTBLM
SCHEMBL28310912 0.66 TRPA1 (0.47) PTPN5USP1WDR48MEN1APAF1
SCHEMBL12863625 0.65 S1PR1 (0.46) RXRARXRBRXRGPTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969436-B2 Method of producing a molded article TEIJIN CHEMICALS, LTD. (JP) 2015-03-03 US disclosed
US-20110147992-A1 METHOD OF PRODUCING A MOLDED ARTICLE TEIJIN CHEMICALS, LTD. (JP) 2011-06-23 US disclosed