SCHEMBL19959765

SCHEMBL19959765

c1ccc2cc3c(cc2c1)c1c2ccccc2ccc1c1nc2ccccc2n31

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.48
KMT2A Q03164 5/20 0.47
MAPT P10636 5/20 0.47
MEN1 O00255 3/20 0.47
CYP1A2 P05177 2/20 0.47
CAMKK1 Q8N5S9 2/20 0.47
CAMKK2 Q96RR4 2/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CASP1 P29466 1/20 0.47
CYP2C19 P33261 1/20 0.47
CASP7 P55210 1/20 0.47
KDM4E B2RXH2 6/20 0.47
POLB P06746 2/20 0.47
LMNA P02545 2/20 0.47
TP53 P04637 2/20 0.47
HSD17B10 Q99714 2/20 0.47
NPC1 O15118 2/20 0.46
CYP3A4 P08684 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19959760 0.89 KDM4E (0.43) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL18118549 0.88 BCL2 (0.52) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL25612734 0.87 BCL2 (0.49) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL14643738 0.85 HPGD (0.47) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL18118574 0.85 HPGD (0.49) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL18374561 0.85 KDM4E (0.50) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL14644805 0.85 AHR (0.53) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL21791146 0.84 KDM4E (0.39) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL14643514 0.84 HPGD (0.43) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL21298227 0.84 BCL2 (0.43) BCL2KMT2AMAPTMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 BCL2 2578/4885KMT2A 443/4885MAPT 1310/4885
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS BCL2 4389/4885KMT2A 1893/4885MAPT 467/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS BCL2 4389/4885KMT2A 1893/4885MAPT 467/4885
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 BCL2 2578/4885KMT2A 443/4885MAPT 1310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.