Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709426 | 0.85 | KMT2A (0.43) | KMT2APKMOPRM1LMNAKDM4E | |
| SCHEMBL8705961 | 0.84 | KMT2A (0.44) | KMT2APKMHSD11B1LMNAKDM4E | |
| SCHEMBL8704499 | 0.84 | OPRM1 (0.39) | KMT2AOPRM1OPRK1OPRL1BRD4 | |
| SCHEMBL8701494 | 0.81 | LMNA (0.42) | KMT2APKMHSD11B1LMNAKDM4E | |
| SCHEMBL8706705 | 0.81 | OPRM1 (0.39) | KMT2AOPRM1OPRK1OPRL1BRD4 | |
| Hydrochloric Acid SCHEMBL8708080 | 0.75 | CCR1 (0.47) | KMT2AOPRL1 | |
| SCHEMBL2825194 | 0.74 | KMT2A (0.48) | KMT2APKMBRD4HSD11B1LMNA | |
| SCHEMBL8702104 | 0.73 | SIGMAR1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL8702126 | 0.72 | SIGMAR1 (0.47) | — | |
| SCHEMBL8709417 | 0.69 | ALDH1A1 (0.39) | KMT2AOPRM1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |