Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TACR3 | P29371 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KDM6B | O15054 | 3/20 | 0.47 |
| ▸ | KDM5C | P41229 | 3/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.47 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19961308 | 0.86 | ALDH1A1 (0.67) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL19961309 | 0.79 | RAB9A (0.65) | ALDH1A1POLBLMNARAB9AKDM5A | |
| SCHEMBL19961310 | 0.78 | PARP1 (0.44) | ALDH1A1POLBTACR3L3MBTL1KDM4E | |
| SCHEMBL2134171 | 0.78 | ALDH1A1 (1.00) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL19961319 | 0.76 | ALDH1A1 (0.63) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL1739264 | 0.73 | KDM5A (0.46) | KDM5A | |
| SCHEMBL19658655 | 0.72 | MAPK11 (0.53) | ALDH1A1POLBKDM5AKDM4E | |
| SCHEMBL1828872 | 0.72 | ALDH1A1 (0.68) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL12489580 | 0.72 | ALDH1A1 (0.68) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL16973965 | 0.72 | ALDH1A1 (0.68) | ALDH1A1POLBTACR3LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072666-A1 | ENOYL REDUCTASE INHIBITORS WITH ANTIBACTERIAL ACTIVITY | NOVALEX THERAPEUTICS INC (US) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072666-A1 | ENOYL REDUCTASE INHIBITORS WITH ANTIBACTERIAL ACTIVITY | FAR1, TECR, ECI1 | ALDH1A1 1739/4885POLB 1742/4885TACR3 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.