Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | TACR3 | P29371 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SPR | P35270 | 1/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.50 |
| ▸ | KDM6B | O15054 | 2/20 | 0.49 |
| ▸ | KDM5C | P41229 | 2/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19961320 | 0.86 | ALDH1A1 (0.63) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL2806341 | 0.84 | HSD11B1 (0.60) | ALDH1A1POLBRAB9AHSD11B1SPR | |
| SCHEMBL19961370 | 0.83 | ALDH1A1 (0.58) | ALDH1A1POLBHSD11B1KDM4ESPR | |
| SCHEMBL19404912 | 0.81 | GRIN2B (0.58) | RAB9AHSD11B1SPRUSP30 | |
| SCHEMBL2134171 | 0.81 | ALDH1A1 (1.00) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL15755587 | 0.80 | HPGD (0.65) | ALDH1A1LMNARAB9AL3MBTL1KDM4E | |
| SCHEMBL29640084 | 0.80 | HSD11B1 (0.59) | POLBHSD11B1SPRUSP30KDM5A | |
| SCHEMBL19961319 | 0.79 | ALDH1A1 (0.63) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL4074303 | 0.78 | HSD11B1 (0.53) | HSD11B1SPRUSP30KDM5A | |
| SCHEMBL19961306 | 0.78 | RAB9A (0.69) | ALDH1A1POLBLMNARAB9AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072666-A1 | ENOYL REDUCTASE INHIBITORS WITH ANTIBACTERIAL ACTIVITY | NOVALEX THERAPEUTICS INC (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180072666-A1 | ENOYL REDUCTASE INHIBITORS WITH ANTIBACTERIAL ACTIVITY | NOVALEX THERAPEUTICS INC (US) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072666-A1 | ENOYL REDUCTASE INHIBITORS WITH ANTIBACTERIAL ACTIVITY | FAR1, TECR, ECI1 | ALDH1A1 1739/4885POLB 1742/4885TACR3 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.