Pyrene

Pyrene

SCHEMBL1996138

c1cc2ccc3cccc4ccc(c1)c2c34.c1ccc2ccccc2c1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.85
HSD17B10 Q99714 7/20 0.85
TSHR P16473 6/20 0.85
CYP1A2 P05177 5/20 0.85
HPGD P15428 4/20 0.85
CYP3A4 P08684 4/20 0.85
CYP1A1 P04798 2/20 0.85
CYP1B1 Q16678 2/20 0.85
CYP2A6 P11509 6/20 0.61
ALOX12 P18054 1/20 0.61
THRB P10828 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.56
MAPK1 P28482 2/20 0.56
ATM Q13315 1/20 0.56
ERBB2 P04626 1/20 0.52
FYN P06241 1/20 0.52
MAOA P21397 1/20 0.52
ACHE P22303 1/20 0.52
AHR P35869 1/20 0.52
TDP1 Q9NUW8 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL27737703 0.96 ALDH1A1 (0.79) ALDH1A1HSD17B10TSHRCYP1A2HPGD
Pyrene SCHEMBL29429699 0.92 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRCYP1A2HPGD
SCHEMBL31298365 0.92 ALDH1A1 (0.83) ALDH1A1HSD17B10TSHRCYP1A2HPGD
Pyrene SCHEMBL1650929 0.92 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRCYP1A2HPGD
Pyrene SCHEMBL223412 0.92 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRCYP1A2HPGD
SCHEMBL1704742 0.92 ALDH1A1 (0.83) ALDH1A1HSD17B10TSHRCYP1A2HPGD
Pyrene SCHEMBL1332849 0.92 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRCYP1A2HPGD
Pyrene SCHEMBL9130 0.92 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRCYP1A2HPGD
Pyrene SCHEMBL23319293 0.88 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRCYP1A2HPGD
Pyrene SCHEMBL1275551 0.88 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRCYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110204691-B Nanobelt based on fused ring graphene and preparation method 南京邮电大学 2021-11-12 CN claimed
CN-110204691-A One kind being based on condensed ring graphene nanobelt and preparation method 南京邮电大学 2019-09-06 CN claimed
US-20240077837-A1 SYSTEMS AND METHODS FOR INDICATING THE TIME ELAPSED SINCE THE OCCURRENCE OF A TRIGGERING EVENT JOHNSON & JOHNSON VISION CARE (US) 2024-03-07 US disclosed
US-11853013-B2 Systems and methods for indicating the time elapsed since the occurrence of a triggering event JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-12-26 US disclosed
EP-4165465-A1 SYSTEMS AND METHODS FOR INDICATING THE TIME ELAPSED SINCE THE OCCURRENCE OF A TRIGGERING EVENT Johnson & Johnson Vision Care, Inc. (US) 2023-04-19 EP disclosed
WO-2021255536-A1 SYSTEMS AND METHODS FOR INDICATING THE TIME ELAPSED SINCE THE OCCURRENCE OF A TRIGGERING EVENT JOHNSON & JOHNSON VISION CARE, INC. (US) 2021-12-23 WO disclosed
US-20210389731-A1 SYSTEMS AND METHODS FOR INDICATING THE TIME ELAPSED SINCE THE OCCURRENCE OF A TRIGGERING EVENT JOHNSON & JOHNSON VISION CARE, INC. 2021-12-16 US disclosed
CN-110204691-B Nanobelt based on fused ring graphene and preparation method 南京邮电大学 2021-11-12 CN disclosed
EP-3728513-A1 POLYMERIZATION COMPOSITION FOR PRODUCING A SCINTILLATING HYBRID MATERIAL AND ASSOCIATED KITS Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2020-10-28 EP disclosed
EP-3728514-A1 SCINTILLATING HYBRID MATERIAL, ASSOCIATED PART, ASSOCIATED DEVICE AND ASSOCIATED APPARATUS, METHODS FOR PRODUCING OR MEASURING SAME Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2020-10-28 EP disclosed
CN-110204691-A One kind being based on condensed ring graphene nanobelt and preparation method 南京邮电大学 2019-09-06 CN disclosed
CN-106282057-B Bacterial strain capable of degrading polycyclic aromatic hydrocarbon and application thereof 台州职业技术学院 2019-05-28 CN disclosed
CN-106282057-A Bacterial strain capable of degrading polycyclic aromatic hydrocarbon and application thereof 台州职业技术学院 2017-01-04 CN disclosed
CN-105658606-A Anthracene compound; light-emitting-layer material; and organic electroluminescent element, display device, and illumination device using same 捷恩智株式会社 2016-06-08 CN disclosed
US-9010318-B2 Extended-range heat transfer fluid using variable composition WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-04-21 US disclosed
US-20110146959-A1 EXTENDED-RANGE HEAT TRANSFER FLUID USING VARIABLE COMPOSITION WISCONSIN ALUMNI RESEARCH FOUNDATION 2011-06-23 US disclosed
WO-2009056344-A1 CORE-SHELL MACROMOLECULES FOR SPECIFIC CELL NUCLEUS OR/AND CELL MATRIX STAINING MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2009-05-07 WO disclosed
EP-1440105-B1 PARTICULATE HYDROPHOBIC POLYMER, PRODUCTION PROCESS THEREFOR AND COLUMN FOR REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY SHOWA DENKO KK (JP) 2006-12-27 EP disclosed
CN-1046178-A A kind of oil-saving agent ZHAN XIAOLING (CN) 1990-10-17 CN disclosed
US-4465833-A ALKYNYLATION HALOGENATED BENZENE COMPOUND IN PRESENCE OF METAL CATALYST HUGHES AIRCRAFT COMPANY (US) 1984-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11853013-B2 Systems and methods for indicating the time elapsed since the occurrence of a triggering event MTREX, CD63, CASP6 ALDH1A1 4471/4885HSD17B10 4323/4885TSHR 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.