Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.45 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416407 | 0.90 | PLK1 (0.50) | PLK1GAACXCR2MTNR1AALOX5 | |
| SCHEMBL3365582 | 0.89 | TERT (0.59) | PLK1GAACXCR2MTNR1AALOX5 | |
| SCHEMBL23879783 | 0.88 | PLK1 (0.49) | PLK1GAACXCR2MTNR1AALOX5 | |
| SCHEMBL14310585 | 0.87 | ALDH1A1 (0.62) | PLK1GAACXCR2KDM4EALDH1A1 | |
| SCHEMBL23879779 | 0.87 | PLK1 (0.47) | PLK1GAACXCR2MTNR1AALOX5 | |
| SCHEMBL23153389 | 0.87 | PLK1 (0.47) | PLK1GAACXCR2MTNR1AALOX5 | |
| SCHEMBL23879805 | 0.87 | PLK1 (0.47) | PLK1GAACXCR2MTNR1ABRD4 | |
| SCHEMBL12260753 | 0.86 | MMP2 (0.60) | PLK1GAACXCR2MTNR1ABRD4 | |
| SCHEMBL17544377 | 0.82 | TAS1R3 (0.61) | PLK1MTNR1AKDM4EALDH1A1HPGD | |
| SCHEMBL7194219 | 0.82 | ERN1 (0.50) | PLK1GAACXCR2MTNR1AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051968-B1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | UNIV CALIFORNIA (US) | 2020-04-29 | — | — | EP | disclosed |
| WO-2018048879-A1 | METAL CHELATORS FOR IMAGING, THERAPEUTICS, AND BIOANALYSIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-03-15 | — | — | WO | disclosed |