Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | PLK1 | P53350 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19962170 | 0.89 | PLK1 (0.59) | TERTALOX5PLK1GAACXCR2 | |
| SCHEMBL26296693 | 0.85 | SELL (0.56) | TERTALOX5PLK1GAAKDM4E | |
| SCHEMBL1799299 | 0.83 | KDM4E (0.65) | PLK1GAAKDM4EMPOSMN1; SMN2 | |
| SCHEMBL4229962 | 0.83 | TERT (0.63) | TERTALOX5GAAKDM4EMPO | |
| SCHEMBL14164188 | 0.82 | PLK1 (0.52) | TERTALOX5PLK1GAACXCR2 | |
| SCHEMBL14310585 | 0.82 | ALDH1A1 (0.62) | PLK1GAACXCR2KDM4ESMN1; SMN2 | |
| SCHEMBL723254 | 0.81 | TERT (0.61) | TERTALOX5GAAKDM4EMPO | |
| SCHEMBL32018464 | 0.81 | TERT (0.61) | TERTALOX5GAAKDM4EMPO | |
| SCHEMBL1436240 | 0.81 | GAA (0.69) | TERTALOX5GAAKDM4EMPO | |
| SCHEMBL24445885 | 0.80 | GAA (0.58) | TERTALOX5PLK1GAACXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941452-A1 | SMALL MOLECULES TARGETING THE INTRINSICALLY DISORDERED STRUCTURAL ENSEMBLE OF ALPHA-SYNUCLEIN PROTECT AGAINST DIVERSE ALPHA-SYNUCLEIN MEDIATED DYSFUNCTIONS | The Regents of the University of California (US) | 2022-01-26 | — | — | EP | claimed |
| WO-2020190970-A1 | SMALL MOLECULES TARGETING THE INTRINSICALLY DISORDERED STRUCTURAL ENSEMBLE OF ALPHA-SYNUCLEIN PROTECT AGAINST DIVERSE ALPHA-SYNUCLEIN MEDIATED DYSFUNCTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-09-24 | — | — | WO | claimed |
| US-8183279-B2 | 1,3-dihydroisoindole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-22 | — | — | US | claimed |
| US-20100311745-A1 | 1,3-DIHYDROISOINDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-09 | — | — | US | claimed |
| WO-2021007441-A1 | CONTAMINANT REMEDIATION WITH FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND SYSTEMS RELATED THERETO | COUNTERTRACE LLC (US) | 2021-01-14 | — | — | WO | disclosed |
| CN-108884021-A | Novel compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof and medical use thereof | 启明大学校产学协力团 | 2018-11-23 | — | — | CN | disclosed |
| US-10039836-B2 | Polyamine-dihydroxybenzoic acid conjugate hydrogels as iron chelators | THE UNIVERSITY OF KANSAS (US) | 2018-08-07 | — | — | US | disclosed |
| US-20170028072-A1 | POLYAMINE-DIHYDROXYBENZOIC ACID CONJUGATE HYDROGELS AS IRON CHELATORS | THE UNIVERSITY OF KANSAS | 2017-02-02 | — | — | US | disclosed |
| CN-101790513-A | 1,3-dihydroisoindole derivatives | MERCK PATENT GMBH | 2010-07-28 | — | — | CN | disclosed |
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| JP-2008214251-A | LYSINE DERIVATIVE AND ITS BASAL MEMBRANE INFILTRATION INHIBITOR | TOYAMA PREFECTURE | 2008-09-18 | — | — | JP | disclosed |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) | 2008-07-03 | — | — | US | disclosed |
| WO-2008043911-A2 | DENDRITIC CHELATED COMPOUNDS, METHODS FOR MAKING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | disclosed |
| US-4855140-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | TERT 1922/4885ALOX5 3876/4885PLK1 3354/4885 |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | HAVCR2, EIF2AK2, RNASE1 | TERT 244/4885ALOX5 2969/4885PLK1 3565/4885 |
| US-20100311745-A1 | 1,3-DIHYDROISOINDOLE DERIVATIVES | HSP90AB1, HSP90AA1, HSP90AB2P | TERT 3632/4885ALOX5 4747/4885PLK1 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.