Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | MLYCD | O95822 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23706343 | 0.85 | FPR2 (0.41) | ADORA3ADORA2AADORA2BADORA1FPR2 | |
| SCHEMBL18106170 | 0.83 | SMN1; SMN2 (0.45) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL2490033 | 0.80 | FDPS (0.43) | ALDH1A1KMT2AMEN1RAB9ATSHR | |
| SCHEMBL24858575 | 0.76 | BRD4 (0.36) | ADORA3ADORA2AADORA2BADORA1NR3C1 | |
| SCHEMBL23043665 | 0.75 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL19827148 | 0.74 | GAA (0.44) | ALDH1A1KMT2AMEN1RAB9ATSHR | |
| SCHEMBL14254645 | 0.73 | KCNH2 (0.35) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL4898433 | 0.73 | MC4R (0.35) | ADORA3ADORA2AADORA2BADORA1FPR2 | |
| SCHEMBL16136347 | 0.73 | FPR2 (0.49) | ADORA3ADORA2AADORA2BADORA1KMT2A | |
| SCHEMBL4888356 | 0.72 | ADORA3 (0.33) | ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253014-B2 | Cyclic amine derivative and pharmaceutical use thereof | TORAY INDUSTRIES, INC. (JP) | 2019-04-09 | — | — | US | disclosed |
| US-20180072701-A1 | CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072701-A1 | CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | SLC10A1, MC2R, ADRA1D | ADORA3 69/4885ADORA2A 111/4885ADORA2B 87/4885 |
| US-10253014-B2 | Cyclic amine derivative and pharmaceutical use thereof | SLC10A1, MC2R, ADRA1D | ADORA3 69/4885ADORA2A 111/4885ADORA2B 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.