SCHEMBL1997013

SCHEMBL1997013

O=COc1cc(F)ccc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
NFE2L2 Q16236 4/20 0.35
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ERN1 O75460 1/20 0.32
HSPB1 P04792 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98914 0.83 ALDH1A1 (0.43) CES2CES1ALDH1A1MEN1KMT2A
SCHEMBL29068866 0.81 EPAS1 (0.38) ALDH1A1MAPTTDP1ERN1
SCHEMBL18068141 0.79 DGAT1 (0.36) ALDH1A1MEN1KMT2AHPGDMAPT
SCHEMBL19268065 0.79 ALDH1A1 (0.47) ALDH1A1MEN1KMT2APOLBHPGD
SCHEMBL27792581 0.79 FFAR1 (0.41) ALDH1A1MEN1KMT2APOLBHPGD
SCHEMBL24445914 0.79 CA3 (0.40) CA3CA6CA5ACA9CA14
SCHEMBL3160079 0.79 FFAR1 (0.41) ERN1
SCHEMBL15759395 0.78 CA3 (0.38) CES2CES1CA3CA6CA5A
SCHEMBL1547855 0.78 CA3 (0.38) CES2CES1CA3CA6CA5A
SCHEMBL95849 0.77 NFE2L2 (0.39) NFE2L2ALDH1A1HPGDMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
CN-114656363-A Synthetic method of palladium-catalyzed aromatic ester compound 南京林业大学 2022-06-24 CN disclosed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed