Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997013 | 0.83 | CES2 (0.39) | ALDH1A1MEN1HPGDKMT2APOLB | |
| SCHEMBL18869467 | 0.80 | TAAR1 (0.44) | — | |
| SCHEMBL10575217 | 0.79 | PKM (0.54) | ALDH1A1MEN1KMT2APOLBHTT | |
| SCHEMBL27889648 | 0.79 | MRGPRX4 (0.40) | ALDH1A1MEN1HPGDKMT2APOLB | |
| SCHEMBL14864481 | 0.79 | MRGPRX4 (0.40) | ALDH1A1HTT | |
| SCHEMBL9775676 | 0.79 | SLC6A2 (0.41) | ALDH1A1MEN1HPGDKMT2APOLB | |
| SCHEMBL2091964 | 0.79 | DGAT1 (0.40) | ALDH1A1POLBHTTL3MBTL1TDP1 | |
| SCHEMBL9545003 | 0.78 | HSPB1 (0.39) | ALDH1A1MEN1HPGDKMT2APOLB | |
| SCHEMBL1547575 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MEN1HPGDKMT2APOLB | |
| SCHEMBL95849 | 0.77 | NFE2L2 (0.39) | ALDH1A1HPGDHTTMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438214-A | The preparation method of the bromo- 2,4 difluorobenzene formic acid of high-purity 5- | 大连奇凯医药科技有限公司 | 2019-03-08 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| EP-0354297-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | claimed |
| CN-108623447-A | A kind of synthetic method of medicine intermediate 2,4 difluorobenzene formic acid | 成都中恒华铁科技有限公司 | 2018-10-09 | — | — | CN | disclosed |
| US-9608287-B2 | Non-aqueous electrolytic solution, electrical storage device utilizing same, and cyclic sulfonic acid ester compound | UBE INDUSTRIES, LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| EP-2701230-B1 | NON-AQUEOUS ELECTROLYTE SOLUTION, ELECTRICITY STORAGE DEVICE USING THE SAME, AND TRIFLUOROMETHYLBENZENE COMPOUND | UBE INDUSTRIES (JP) | 2016-11-23 | — | — | EP | disclosed |
| US-9472828-B2 | Nonaqueous electrolyte solution, electricity storage device using same, and trifluoromethylbenzene compound | UBE INDUSTRIES, LTD. (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-2975040-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | Sagami Chemical Research Institute (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-9236635-B2 | Non-aqueous electrolyte and electricity storage device using same | UBE INDUSTRIES, LTD. (JP) | 2016-01-12 | — | — | US | disclosed |
| EP-2043644-A1 | NF- B INHIBITOR | Otsuka Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008010601-A1 | NF- ϰB INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | WO | disclosed |
| US-20070179173-A1 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |
| EP-0354297-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | disclosed |
| US-5021412-A | Protecting agricultural crops | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0354297-A1 | Thiadiazines, process for production thereof, and insecticidal and acaricidal agents comprising the thiadiazines | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-02-14 | — | — | EP | disclosed |
| US-4093812-A | MICROBIOCIDES, DISINFECTANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1978-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | DDT, PDHX, CYP4X1 | ALDH1A1 596/4885MEN1 3576/4885HPGD 2381/4885 |
| US-20070179173-A1 | Carbostyril compound | GTF2F1, F3, GTF2F2 | ALDH1A1 2458/4885MEN1 3912/4885HPGD 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.