Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618728 | 0.84 | HTR6 (0.46) | HTR6DRD2IDEHTR2ABRD4 | |
| SCHEMBL19971366 | 0.84 | HTR6 (0.41) | HTR6DRD2IDEPTGDRPTGDR2 | |
| SCHEMBL19971354 | 0.83 | HTR6 (0.38) | HTR6DRD2IDEPTGDRPTGDR2 | |
| SCHEMBL19971348 | 0.81 | HTR6 (0.36) | HTR6DRD2IDEHTR2ARORC | |
| SCHEMBL16618765 | 0.80 | HTR6 (0.42) | HTR6DRD2IDEPTGDRPTGDR2 | |
| SCHEMBL16626796 | 0.78 | HTR6 (0.39) | HTR6DRD2IDEPTGDRPTGDR2 | |
| SCHEMBL19971401 | 0.76 | HTR6 (0.39) | HTR6IDEPTGDRPTGDR2HDAC1 | |
| SCHEMBL19971533 | 0.76 | HTR6 (0.39) | HTR6IDEPTGDRPTGDR2HTR2A | |
| SCHEMBL19971426 | 0.74 | RORC (0.45) | HTR6HDAC1HDAC2HDAC6BRD4 | |
| SCHEMBL19971361 | 0.74 | HTR6 (0.36) | HTR6DRD2IDEPTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |