Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 5/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971401 | 0.87 | HTR6 (0.39) | HTR6PTGDRPTGDR2PPARGPPARD | |
| SCHEMBL16626660 | 0.86 | HTR6 (0.40) | HTR6BRD4DHODHPTGDRPTGDR2 | |
| Hydrochloric Acid SCHEMBL16619040 | 0.86 | HTR6 (0.39) | HTR6BRD4DHODHPTGDRPTGDR2 | |
| SCHEMBL16618934 | 0.85 | BRD4 (0.38) | HTR6BRD4DHODHPTGDRPTGDR2 | |
| SCHEMBL16626665 | 0.82 | HTR2C (0.35) | HTR6BRD4DHODHPTGDRPTGDR2 | |
| SCHEMBL19971366 | 0.82 | HTR6 (0.41) | HTR6BRD4PTGDRPTGDR2DRD2 | |
| SCHEMBL19971358 | 0.80 | ALK (0.39) | HTR6KMT2A | |
| SCHEMBL17971592 | 0.79 | HTR6 (0.39) | HTR6DHODHPPARGPPARDPPARA | |
| SCHEMBL19971356 | 0.79 | IDE (0.37) | DHODHIDE | |
| SCHEMBL19971348 | 0.78 | HTR6 (0.36) | HTR6PPARGPPARDPPARADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |