SCHEMBL16618751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16619023	0.90	HDAC1 (0.43)	SLC20A2SLC20A1ALOX15RORCHDAC1
	SCHEMBL19971369	0.86	RORC (0.39)	SLC20A2SLC20A1ALOX15RORCMAPT
	SCHEMBL16626748	0.85	RORC (0.38)	SLC20A2SLC20A1ALOX15RORCMAPT
	SCHEMBL16619015	0.85	SLC20A2 (0.38)	SLC20A2SLC20A1ALOX15RORCMAPT
	Hydrochloric Acid SCHEMBL16618931	0.85	RORC (0.38)	SLC20A2SLC20A1ALOX15RORCMAPT
	SCHEMBL16618638	0.83	HTR6 (0.42)	SLC20A2SLC20A1ALOX15RORCHDAC1
	SCHEMBL16619006	0.83	RORC (0.40)	SLC20A2SLC20A1ALOX15POLBRORC
	SCHEMBL16619379	0.83	RORC (0.37)	SLC20A2SLC20A1ALOX15RORCMAPT
	SCHEMBL16619007	0.81	HTR6 (0.42)	POLBNPC1
	SCHEMBL16626659	0.81	RORC (0.37)	SLC20A2SLC20A1RORCHDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.