Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619065 | 0.92 | NR4A2 (0.49) | MEN1KMT2ANR4A2PIK3CAPIK3CG | |
| SCHEMBL19971462 | 0.88 | LMNA (0.43) | MEN1KMT2AAKR1C3AKR1C1PIK3CG | |
| SCHEMBL19971365 | 0.87 | AKR1C3 (0.42) | MEN1KMT2ANR4A2AKR1C3AKR1C1 | |
| SCHEMBL16619135 | 0.82 | HTR6 (0.38) | PIK3CAPIK3CGERN1JAK2JAK1 | |
| SCHEMBL16618580 | 0.81 | NR4A2 (0.50) | MEN1KMT2ANR4A2LMNASMN1; SMN2 | |
| SCHEMBL16618555 | 0.79 | KMT2A (0.52) | MEN1KMT2ANR4A2PIK3CGLMNA | |
| SCHEMBL19971360 | 0.79 | AKR1C3 (0.56) | MEN1KMT2AAKR1C3AKR1C1LMNA | |
| SCHEMBL16618849 | 0.75 | KMT2A (0.56) | MEN1KMT2ANR4A2AKR1C3AKR1C1 | |
| SCHEMBL16990396 | 0.73 | HTR6 (0.47) | MEN1KMT2APIK3CA | |
| SCHEMBL17971571 | 0.72 | HTR6 (0.39) | PIK3CAPIK3CGPTGES2PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |