Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618580 | 0.89 | NR4A2 (0.50) | LMNASMN1; SMN2POLBLIPGCYP11B1 | |
| SCHEMBL19971444 | 0.87 | MEN1 (0.41) | AKR1C3AKR1C1LMNASMN1; SMN2PLK1 | |
| SCHEMBL19971506 | 0.84 | AKR1C3 (0.42) | AKR1C3AKR1C1DHODHLMNASMN1; SMN2 | |
| SCHEMBL19971462 | 0.83 | LMNA (0.43) | AKR1C3AKR1C1LMNASMN1; SMN2CYP11B1 | |
| SCHEMBL19971360 | 0.82 | AKR1C3 (0.56) | AKR1C3AKR1C1LMNASMN1; SMN2PLK1 | |
| SCHEMBL16626771 | 0.80 | HTR6 (0.39) | LIPGCYP11B1CYP11B2HTR6 | |
| Hydrochloric Acid SCHEMBL16618564 | 0.79 | NR1D1 (0.38) | LIPGCYP11B1CYP11B2HTR6 | |
| SCHEMBL16619065 | 0.78 | NR4A2 (0.49) | CYP11B1CYP11B2MEN1KMT2ANR4A2 | |
| SCHEMBL16618555 | 0.74 | KMT2A (0.52) | LMNASMN1; SMN2POLBCYP11B1CYP11B2 | |
| SCHEMBL16619174 | 0.73 | MEN1 (0.45) | LMNASMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |