Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618555 | 0.91 | KMT2A (0.52) | LMNAKMT2AMEN1CHRNB4CHRNA3 | |
| SCHEMBL19971444 | 0.88 | MEN1 (0.41) | LMNAKMT2AMEN1PIK3CGAKR1C3 | |
| SCHEMBL19971365 | 0.83 | AKR1C3 (0.42) | LMNAKMT2AMEN1HTR6AKR1C3 | |
| SCHEMBL16618925 | 0.83 | HTR6 (0.49) | LMNACHRNB4CHRNA3KEAP1NFE2L2 | |
| SCHEMBL19971360 | 0.81 | AKR1C3 (0.56) | LMNAKMT2AMEN1HTR6AKR1C3 | |
| SCHEMBL16626627 | 0.81 | HTR6 (0.46) | LMNACHRNB4CHRNA3KEAP1NFE2L2 | |
| SCHEMBL19971359 | 0.80 | HTR6 (0.42) | LMNAKMT2AMEN1CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL16619326 | 0.80 | HTR6 (0.46) | LMNACHRNB4CHRNA3KEAP1NFE2L2 | |
| SCHEMBL16619065 | 0.79 | NR4A2 (0.49) | KMT2AMEN1PIK3CGCYP11B1CYP11B2 | |
| SCHEMBL28068087 | 0.79 | KMT2A (0.49) | LMNAKMT2AMEN1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |