Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 15/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971426 | 0.81 | RORC (0.45) | RORCHTR6FBP1BRD4 | |
| SCHEMBL16618633 | 0.80 | RORC (0.47) | RORCHTR6DRD2BRD4 | |
| SCHEMBL16626634 | 0.77 | RORC (0.45) | RORCHTR6BRD4 | |
| SCHEMBL4772155 | 0.74 | HTR6 (0.47) | HTR6DRD2 | |
| SCHEMBL19971345 | 0.70 | IDE (0.43) | HTR6DRD2 | |
| SCHEMBL28857516 | 0.70 | IDE (0.41) | HTR6DRD2 | |
| SCHEMBL28449411 | 0.69 | RORC (0.53) | RORCHTR6 | |
| SCHEMBL28207563 | 0.69 | IDE (0.42) | HTR6DRD2 | |
| SCHEMBL29169604 | 0.68 | HTR6 (0.69) | HTR6DRD2 | |
| SCHEMBL21274641 | 0.68 | HTR6 (0.54) | HTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |