SCHEMBL19972211

SCHEMBL19972211

CCCCCCc1ccc(Nc2cccc3ccccc23)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.49
HPGD P15428 3/20 0.49
KDM4E B2RXH2 3/20 0.49
MAPT P10636 2/20 0.49
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 2/20 0.49
GAA P10253 2/20 0.49
USP2 O75604 1/20 0.49
GLA P06280 1/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
TYR P14679 3/20 0.49
KMT2A Q03164 3/20 0.49
TP53 P04637 2/20 0.49
ALOX15 P16050 2/20 0.49
TSHR P16473 2/20 0.49
MEN1 O00255 2/20 0.49
HTT P42858 2/20 0.49
ALOX5 P09917 1/20 0.49
TDP1 Q9NUW8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19979479 0.82 CDC25B (0.46) CYP3A4HPGDKDM4EMAPTALDH1A1
SCHEMBL19986528 0.80 TYR (0.58) CYP3A4HPGDKDM4EMAPTALDH1A1
SCHEMBL293780 0.79 ALDH1A1 (0.54) CYP3A4HPGDKDM4EALDH1A1HSD17B10
SCHEMBL110264 0.79 ALDH1A1 (0.54) CYP3A4HPGDKDM4EALDH1A1HSD17B10
SCHEMBL1705432 0.79 ALDH1A1 (0.54) CYP3A4HPGDKDM4EALDH1A1HSD17B10
SCHEMBL294932 0.79 ALDH1A1 (0.54) CYP3A4HPGDKDM4EALDH1A1HSD17B10
SCHEMBL29382146 0.79 ALDH1A1 (0.54) CYP3A4HPGDKDM4EALDH1A1HSD17B10
SCHEMBL33526666 0.79 SLC16A3 (0.46) CYP3A4HPGDKDM4EMAPTALDH1A1
SCHEMBL9619173 0.79 SLC16A3 (0.46) CYP3A4HPGDKDM4EMAPTALDH1A1
SCHEMBL284843 0.79 SLC16A3 (0.46) CYP3A4HPGDKDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12049599-B2 Alkylated alkoxydiarylamine antioxidants LANXESS CORPORATION (US) 2024-07-30 US disclosed
EP-3516019-B1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS CORP (US) 2023-06-14 EP disclosed
CN-109642176-B Alkylated alkoxy diarylamine antioxidants 朗盛解决方案美国公司 2022-12-30 CN disclosed
EP-3516020-B1 ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS LANXESS CORP (US) 2022-05-25 EP disclosed
US-20200407658-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. (US) 2020-12-31 US disclosed
US-20200407658-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. (US) 2020-12-31 US disclosed
US-10808197-B2 Alkylated alkoxydiarylamine antioxidants LANXESS SOLUTIONS US INC. (US) 2020-10-20 US disclosed
US-10808197-B2 Alkylated alkoxydiarylamine antioxidants LANXESS SOLUTIONS US INC. (US) 2020-10-20 US disclosed
US-10723969-B2 Lubricant compositions stabilized by mixtures of diarylamine and hydroxydiarylamine antioxidants LANXESS SOLUTIONS US INC. (US) 2020-07-28 US disclosed
EP-3516018-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS Lanxess Solutions US Inc. (US) 2019-07-31 EP disclosed
WO-2018057365-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. (US) 2018-03-29 WO disclosed
WO-2018057365-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. (US) 2018-03-29 WO disclosed
WO-2018057366-A1 ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. (US) 2018-03-29 WO disclosed
WO-2018057364-A1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. (US) 2018-03-29 WO disclosed
US-20180079987-A1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. 2018-03-22 US disclosed
US-20180079984-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS LANXESS CORPORATION 2018-03-22 US disclosed
US-20180079984-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS LANXESS CORPORATION 2018-03-22 US disclosed
US-20180079985-A1 ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. 2018-03-22 US disclosed
US-20180079987-A1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. 2018-03-22 US disclosed
US-20180079984-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS LANXESS CORPORATION 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10808197-B2 Alkylated alkoxydiarylamine antioxidants GPX4, CAT, SOD1 CYP3A4 403/4885HPGD 601/4885KDM4E 1996/4885
US-20200407658-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS GPX4, CAT, SOD1 CYP3A4 403/4885HPGD 601/4885KDM4E 1996/4885
US-12049599-B2 Alkylated alkoxydiarylamine antioxidants GPX4, CAT, SOD1 CYP3A4 403/4885HPGD 601/4885KDM4E 1996/4885
US-20180079984-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS GPX4, CAT, SOD1 CYP3A4 403/4885HPGD 601/4885KDM4E 1996/4885
US-20180079985-A1 ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS GPX4, GSTO1, LPO CYP3A4 478/4885HPGD 97/4885KDM4E 1768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.