Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 9/20 | 0.53 |
| ▸ | FPR2 | P25090 | 6/20 | 0.43 |
| ▸ | CPS1 | P31327 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19972255 | 0.83 | FPR1 (0.57) | FPR1FPR2CPS1QDPRMTNR1A | |
| SCHEMBL19972257 | 0.83 | FPR1 (0.57) | FPR1FPR2CPS1QDPRMTNR1A | |
| SCHEMBL19985877 | 0.83 | FPR1 (0.57) | FPR1FPR2CPS1QDPRMTNR1A | |
| Hydrochloric Acid SCHEMBL19972353 | 0.82 | FPR1 (0.56) | FPR1FPR2CPS1QDPRMTNR1A | |
| Hydrochloric Acid SCHEMBL19972350 | 0.82 | FPR1 (0.56) | FPR1FPR2CPS1QDPRMTNR1A | |
| SCHEMBL19972293 | 0.77 | FPR1 (0.69) | FPR1FPR2 | |
| SCHEMBL19994133 | 0.75 | FPR1 (0.51) | FPR1FPR2 | |
| SCHEMBL20001240 | 0.73 | FPR1 (0.64) | FPR1FPR2PDE4B | |
| SCHEMBL19988375 | 0.73 | FPR1 (0.64) | FPR1FPR2PDE4B | |
| SCHEMBL19972243 | 0.70 | FPR1 (0.83) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10265310-B2 | 6-membered cyclic amines or lactames substituted with urea and phenyl | Grünenthal GmbH (DE) | 2019-04-23 | — | — | US | disclosed |
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | FPR1 2/4885FPR2 1/4885CPS1 1497/4885 |
| US-10265310-B2 | 6-membered cyclic amines or lactames substituted with urea and phenyl | FPR2, FPR1, FPR3 | FPR1 2/4885FPR2 1/4885CPS1 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.