Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995225 | 0.79 | REN (0.54) | FPR1 | |
| SCHEMBL19972372 | 0.77 | FPR1 (0.69) | FPR1FPR2 | |
| SCHEMBL19972360 | 0.75 | FPR1 (0.53) | FPR1FPR2 | |
| SCHEMBL23644663 | 0.74 | FPR2 (0.53) | FPR1FPR2 | |
| SCHEMBL20001242 | 0.71 | FPR1 (0.62) | FPR1FPR2 | |
| SCHEMBL19988703 | 0.71 | FPR1 (0.62) | FPR1FPR2 | |
| SCHEMBL19988381 | 0.71 | FPR1 (0.62) | FPR1FPR2 | |
| SCHEMBL28867557 | 0.68 | HTR3A (0.36) | — | |
| SCHEMBL28920829 | 0.68 | HTR3A (0.36) | — | |
| SCHEMBL19972281 | 0.68 | FPR1 (1.00) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515902-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018054549-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-29 | — | — | WO | disclosed |