SCHEMBL1997238

SCHEMBL1997238

CC(C)(C)OC(=O)NCC(=O)N1CCC[C@H]1C(=O)OCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 12/20 0.64
PREP P48147 2/20 0.57
KLK5 Q9Y337 1/20 0.55
ACE P12821 2/20 0.52
KLK7 P49862 1/20 0.49
CTSL P07711 1/20 0.49
SIGMAR1 Q99720 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1997241 1.00 FKBP1A (0.64) FKBP1APREPKLK5ACEKLK7
SCHEMBL6787227 1.00 FKBP1A (0.64) FKBP1APREPKLK5ACEKLK7
SCHEMBL7295710 0.92 PREP (0.62) FKBP1APREPKLK5ACEKLK7
SCHEMBL2082597 0.89 PREP (0.69) FKBP1APREPACE
SCHEMBL6605416 0.87 FKBP1A (0.49) FKBP1APREPKLK5
SCHEMBL31049706 0.85 ADORA3 (0.57) FKBP1APREPKLK5ACECTSL
SCHEMBL9464405 0.85 PREP (0.67) FKBP1APREPKLK5ACE
SCHEMBL18620837 0.85 PREP (0.67) FKBP1APREPKLK5ACE
SCHEMBL159105 0.84 KLK7 (0.66) FKBP1APREPKLK5KLK7
SCHEMBL5970730 0.84 KLK7 (0.66) FKBP1APREPKLK5KLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118684727-A GPRP series peptide modified dabigatran derivative, synthesis, activity and application thereof 首都医科大学 2024-09-24 CN claimed
CN-118620088-A Trimer of Asn-Gly-Pro, preparation and application thereof 首都医科大学 2024-09-10 CN claimed
US-12528834-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2026-01-20 US disclosed
CN-118684727-A GPRP series peptide modified dabigatran derivative, synthesis, activity and application thereof 首都医科大学 2024-09-24 CN disclosed
CN-118620088-A Trimer of Asn-Gly-Pro, preparation and application thereof 首都医科大学 2024-09-10 CN disclosed
CN-113929735-B Gly-Pro-Arg-Pro-NHCH 2 CH 2 NH-warfarin, its synthesis, activity and use 首都医科大学 2023-08-01 CN disclosed
US-20220372069-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-11-24 US disclosed
EP-4036103-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND Nissan Chemical Corporation (JP) 2022-08-03 EP disclosed
CN-114401978-A Method for producing peptide compound 日产化学株式会社 2022-04-26 CN disclosed
CN-109111502-B 1, 1-dihydroxymethyl-tetrahydro-beta-carboline-3-formyl-GGPRP, and synthesis, activity and application thereof 首都医科大学 2022-04-22 CN disclosed
WO-2021060048-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND 日産化学株式会社 2021-04-01 WO disclosed
US-8362068-B2 5,5-fused arylene or heteroarylene hepatitis C virus inhibitors IDENIX PHARMACEUTICALS, INC. (US) 2013-01-29 US disclosed
US-20120252721-A1 METHODS FOR TREATING DRUG-RESISTANT HEPATITIS C VIRUS INFECTION WITH A 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITOR IDENIX PHARMACEUTICALS, INC. (US) 2012-10-04 US disclosed
US-20110150827-A1 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITORS IDENIX PHARMACEUTICALS, INC. (US) 2011-06-23 US disclosed
US-4971993-A HYPOTENSIVE DIPEPTIDES DERIVATIVES AJINOMOTO CO., INC. (JP) 1990-11-20 US disclosed
EP-0190852-A2 Dipeptide derivatives and antihypertensive drugs containing them AJINOMOTO CO., INC. (JP) 1986-08-13 EP disclosed
US-4590178-A DIURETICS AJINOMOTO COMPANY, INCORPORATED (JP) 1986-05-20 US disclosed
US-4536395-A DIPEPTIDES AJINOMOTO CO., INC. (JP) 1985-08-20 US disclosed
US-4472381-A Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them AJINOMOTO COMPANY INCORPORATED (JP) 1984-09-18 US disclosed
EP-0085488-A2 Amino acid derivatives and antihypertensive drugs containing them AJINOMOTO CO., INC. (JP) 1983-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110150827-A1 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITORS HAVCR2, CYP3A5, CYP2E1 FKBP1A 1317/4885PREP 1133/4885KLK5 2911/4885
US-12528834-B2 Method for producing peptide compound VIP, IAPP, NPPA FKBP1A 2713/4885PREP 91/4885KLK5 1202/4885
US-20220372069-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND VIP, NPPA, NGLY1 FKBP1A 1695/4885PREP 31/4885KLK5 1690/4885
US-20120252721-A1 METHODS FOR TREATING DRUG-RESISTANT HEPATITIS C VIRUS INFECTION WITH A 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITOR HAVCR2, CYP3A5, CYP7A1 FKBP1A 895/4885PREP 663/4885KLK5 1281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.