Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25239580 | 0.80 | ALDH1A1 (0.40) | KMT2AMAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL16369606 | 0.77 | NPC1 (0.34) | MAPTLMNAL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL1461967 | 0.76 | KMT2A (0.41) | KMT2AMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL19972848 | 0.74 | L3MBTL1 (0.36) | KMT2AMAPTL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL15903547 | 0.71 | HPRT1 (0.44) | KMT2AMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL19972850 | 0.70 | KMT2A (0.51) | KMT2AMAPTLMNAPOLBALDH1A1 | |
| SCHEMBL22362035 | 0.67 | KMT2A (0.67) | HSD11B1KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL15903797 | 0.67 | HPRT1 (0.41) | KMT2AMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL31464018 | 0.67 | ALDH1A1 (0.46) | KMT2AMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15903864 | 0.66 | NCEH1 (0.39) | KMT2AMAPTLMNAL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053321-A1 | PARTICLES, COMPOSITIONS, AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | KALA PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | claimed |
| WO-2018053321-A1 | PARTICLES, COMPOSITIONS, AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | KALA PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |