Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19972850 | 0.83 | KMT2A (0.51) | KMT2AMAPTMEN1HSD17B10ESR1 | |
| SCHEMBL25239580 | 0.81 | ALDH1A1 (0.40) | KMT2AMAPTMEN1USP2SMN1; SMN2 | |
| SCHEMBL15903547 | 0.79 | HPRT1 (0.44) | KMT2AMAPTMEN1TDP1USP2 | |
| SCHEMBL16369606 | 0.78 | NPC1 (0.34) | MAPTSMN1; SMN2NPSR1HPGDLMNA | |
| SCHEMBL15903864 | 0.76 | NCEH1 (0.39) | KMT2AMAPTMEN1TDP1USP2 | |
| SCHEMBL19972854 | 0.76 | HSD11B1 (0.37) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19972848 | 0.76 | L3MBTL1 (0.36) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28825903 | 0.76 | MAPT (0.36) | KMT2AMAPTMEN1TDP1PTGES | |
| SCHEMBL15903797 | 0.74 | HPRT1 (0.41) | KMT2AMAPTMEN1TDP1USP2 | |
| SCHEMBL1461844 | 0.73 | HPRT1 (0.50) | KMT2AMAPTMEN1TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029639-A2 | COMPOUNDS AND METHODS FOR TREATING NEOPLASIA | MEDEXIS S.A. (GR) | 2011-03-17 | — | — | WO | disclosed |