Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25239580 | 0.82 | ALDH1A1 (0.40) | SMN1; SMN2MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL16369606 | 0.78 | NPC1 (0.34) | L3MBTL1SMN1; SMN2PTPN1MAPTHPGD | |
| SCHEMBL1461967 | 0.76 | KMT2A (0.41) | SMN1; SMN2MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL19972854 | 0.74 | HSD11B1 (0.37) | L3MBTL1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL19972850 | 0.74 | KMT2A (0.51) | MAPK1ALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL27291846 | 0.72 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL15903547 | 0.70 | HPRT1 (0.44) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL15903797 | 0.68 | HPRT1 (0.41) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL30074771 | 0.68 | ALDH1A1 (0.41) | L3MBTL1SMN1; SMN2MAPK1ALDH1A1MEN1 | |
| SCHEMBL15903864 | 0.68 | NCEH1 (0.39) | L3MBTL1SMN1; SMN2MAPK1PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053321-A1 | PARTICLES, COMPOSITIONS, AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | KALA PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | claimed |
| WO-2018053321-A1 | PARTICLES, COMPOSITIONS, AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | KALA PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |