Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461967 | 0.83 | KMT2A (0.41) | KMT2AHSD17B10ALDH1A1LMNAGAA | |
| SCHEMBL25239580 | 0.77 | ALDH1A1 (0.40) | KMT2AALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL16369606 | 0.76 | NPC1 (0.34) | LMNAMAPTCSNK1DHPGD | |
| SCHEMBL19972848 | 0.74 | L3MBTL1 (0.36) | KMT2AALDH1A1MEN1MAPTHPGD | |
| SCHEMBL15903547 | 0.73 | HPRT1 (0.44) | KMT2AHSD17B10ALDH1A1LMNAKDM4E | |
| SCHEMBL15903864 | 0.73 | NCEH1 (0.39) | KMT2AALDH1A1LMNAGAAKDM4E | |
| SCHEMBL15903797 | 0.71 | HPRT1 (0.41) | KMT2AHSD17B10ALDH1A1LMNAGAA | |
| SCHEMBL28063309 | 0.71 | KMT2A (0.78) | KMT2AHSD17B10ALDH1A1LMNAKDM4E | |
| SCHEMBL19972854 | 0.70 | HSD11B1 (0.37) | KMT2AALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL1461844 | 0.69 | HPRT1 (0.50) | KMT2AHSD17B10ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053321-A1 | PARTICLES, COMPOSITIONS, AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | KALA PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | claimed |