SCHEMBL19973142

SCHEMBL19973142

Cn1c(-c2ccc(OC(F)(F)F)cc2)cnc1C(=O)CCl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP1A1 P05023 1/20 0.47
ATP1B1 P05026 1/20 0.47
ATP1A3 P13637 1/20 0.47
ATP1B2 P14415 1/20 0.47
ATP1A2 P50993 1/20 0.47
ATP1B3 P54709 1/20 0.47
FXYD2 P54710 1/20 0.47
ATP1A4 Q13733 1/20 0.47
GRIN2B Q13224 1/20 0.41
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
HRH2 P25021 1/20 0.39
HRH1 P35367 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 2/20 0.39
SCN10A Q9Y5Y9 1/20 0.38
GCGR P47871 4/20 0.38
KDM5A P29375 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19981360 0.84 ATP1A1 (0.43) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL19981359 0.84 ATP1A1 (0.43) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL19981361 0.82 ATP1A1 (0.42) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL18355797 0.79 LMNA (0.50) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL24238509 0.78 ATP1A1 (0.49) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL21182237 0.76 ATP1A1 (0.45) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL24460261 0.74 ATP1A1 (0.55) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL28754520 0.74 ATP1A1 (0.40) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL2378872 0.69 MMP2 (0.54) MMP2MMP9MMP8HDAC3HDAC4
SCHEMBL18113755 0.69 MEN1 (0.46) GRIN2BMEN1KMT2ASCN10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
WO-2024034565-A1 IMIDAZOLYLAZOLE COMPOUND AND PEST CONTROL AGENT 日本曹達株式会社 2024-02-15 WO disclosed
CN-109689630-B Diaryl azole compound and pest control agent 日本曹达株式会社 2022-06-03 CN disclosed
EP-3514146-B1 DIARYL- AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO (JP) 2022-03-16 EP disclosed
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2022-02-03 US disclosed
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2022-02-03 US disclosed
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
EP-3514146-A1 DIARYL AZOLE COMPOUND AND PESTICIDE Nippon Soda Co., Ltd. (JP) 2019-07-24 EP disclosed
EP-3514146-A1 DIARYL AZOLE COMPOUND AND PESTICIDE Nippon Soda Co., Ltd. (JP) 2019-07-24 EP disclosed
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2019-06-20 US disclosed
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2019-06-20 US disclosed
WO-2018052035-A1 DIARYL AZOLE COMPOUND AND PESTICIDE 日本曹達株式会社 2018-03-22 WO disclosed
WO-2018052035-A1 DIARYL AZOLE COMPOUND AND PESTICIDE 日本曹達株式会社 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L ATP1A1 470/4885ATP1B1 332/4885ATP1A3 569/4885
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L ATP1A1 470/4885ATP1B1 332/4885ATP1A3 569/4885
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L ATP1A1 470/4885ATP1B1 332/4885ATP1A3 569/4885
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L ATP1A1 470/4885ATP1B1 332/4885ATP1A3 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.