SCHEMBL19973625

SCHEMBL19973625

O=C(OCCc1ccccn1)n1ccnc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
CYP3A4 P08684 2/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C9 P11712 2/20 0.49
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CHRM5 P08912 1/20 0.42
CHRM1 P11229 1/20 0.42
CYP1A2 P05177 2/20 0.42
TBXAS1 P24557 1/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
RECQL P46063 1/20 0.41
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19973543 0.86 SMN1; SMN2 (0.50) CYP3A4CYP2D6CYP2C9NPC1RAB9A
SCHEMBL4059533 0.83 P2RX4 (0.48) CYP3A4NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL26597537 0.82 TBXAS1 (0.52) CYP3A4CYP2D6CYP2C9NPC1RAB9A
SCHEMBL12016623 0.82 ALDH1A1 (0.39) CYP2D6CYP2C9MEN1KMT2ACYP1A2
SCHEMBL17520267 0.79 EPHX1 (0.37) CYP2D6TBXAS1LMNA
SCHEMBL6095146 0.78 CYP3A4 (0.42) CYP3A4CYP2D6CYP2C9MEN1KMT2A
SCHEMBL23764025 0.78 LMNA (0.51) NPC1RAB9AMEN1KMT2ATBXAS1
SCHEMBL9269566 0.77 ALDH1A1 (0.37) CYP3A4CYP2D6CYP2C9MEN1KMT2A
SCHEMBL15464597 0.77 ALDH1A1 (0.36) CYP2D6CYP2C9CYP1A2TBXAS1KDM4E
SCHEMBL15465728 0.77 ALDH1A1 (0.36) CYP2D6CYP2C9CYP1A2TBXAS1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250030049-A1 Electrolyte Additives for Secondary Batteries, Non-aqueous Electrolytes for Lithium Secondary Batteries Including the same, and Lithium Secondary Batteries Including the same DUKSAN ELECTERA CO., LTD. (KR) 2025-01-23 US disclosed
EP-4350834-A1 ELECTROLYTE ADDITIVE FOR SECONDARY BATTERY, NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY INCLUDING SAME, AND LITHIUM SECONDARY BATTERY INCLUDING SAME Duksan Electera Co., Ltd. (KR) 2024-04-10 EP disclosed
WO-2024038942-A1 ELECTROLYTE ADDITIVE FOR SECONDARY BATTERY, NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY INCLUDING SAME, AND LITHIUM SECONDARY BATTERY INCLUDING SAME 주식회사 덕산일렉테라 2024-02-22 WO disclosed
EP-3601216-B1 SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDES AND ANALOGS THEREOF, AND METHODS USING SAME FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION ARBUTUS BIOPHARMA CORP (CA) 2023-10-25 EP disclosed
EP-3601216-B1 SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDES AND ANALOGS THEREOF, AND METHODS USING SAME FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION ARBUTUS BIOPHARMA CORP (CA) 2023-10-25 EP disclosed
US-11001564-B2 Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same ARBUTUS BIOPHARMA CORPORATION (CA) 2021-05-11 US disclosed
US-11001564-B2 Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same ARBUTUS BIOPHARMA CORPORATION (CA) 2021-05-11 US disclosed
US-20190225593-A1 SUBSTITUTED CHROMANE-8-CARBOXAMIDE COMPOUNDS AND ANALOGUES THEREOF, AND METHODS USING SAME ARBUTUS BIOPHARMA CORP (CA) 2019-07-25 US disclosed
US-20190225593-A1 SUBSTITUTED CHROMANE-8-CARBOXAMIDE COMPOUNDS AND ANALOGUES THEREOF, AND METHODS USING SAME ARBUTUS BIOPHARMA CORP (CA) 2019-07-25 US disclosed
WO-2018052967-A1 SUBSTITUTED CHROMANE-8-CARBOXAMIDE COMPOUNDS AND ANALOGUES THEREOF, AND METHODS USING SAME ARBUTUS BIOPHARMA, INC. (US) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225593-A1 SUBSTITUTED CHROMANE-8-CARBOXAMIDE COMPOUNDS AND ANALOGUES THEREOF, AND METHODS USING SAME CBX8, HAVCR2, HCCS CA12 385/4885CA1 863/4885CA2 1212/4885
US-11001564-B2 Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same CBX8, HAVCR2, HCCS CA12 385/4885CA1 863/4885CA2 1212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.