SCHEMBL19975009

SCHEMBL19975009

COC(=O)c1ccc(Sc2cnccc2C(=O)OC)c([N+](=O)[O-])c1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.54
LMNA P02545 1/20 0.54
PDE7A Q13946 1/20 0.53
HPGD P15428 2/20 0.52
VCAM1 P19320 1/20 0.47
POLB P06746 2/20 0.47
ALDH1A1 P00352 4/20 0.46
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18381838 0.86 HPGD (0.58) MAPTLMNAPDE7AHPGDVCAM1
SCHEMBL30610315 0.83 MAPT (0.58) MAPTLMNAHPGDVCAM1POLB
SCHEMBL16430875 0.83 MAPT (0.58) MAPTLMNAHPGDVCAM1POLB
SCHEMBL17085945 0.81 HPGD (0.54) MAPTLMNAHPGDVCAM1POLB
SCHEMBL17080227 0.81 HPGD (0.54) MAPTLMNAHPGDVCAM1POLB
SCHEMBL19984746 0.81 ALDH1A1 (0.58) MAPTLMNAPDE7AHPGDPOLB
SCHEMBL30401491 0.81 ALDH1A1 (0.58) MAPTLMNAPDE7AHPGDPOLB
SCHEMBL17080233 0.81 HPGD (0.53) MAPTLMNAPDE7AHPGDVCAM1
SCHEMBL17080117 0.81 HPGD (0.56) MAPTLMNAHPGDVCAM1POLB
SCHEMBL17080225 0.80 SLC6A2 (0.56) MAPTLMNAHPGDVCAM1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250064060-A1 BIS(HETERO)ARYL THIOETHER (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2025-02-27 US claimed
EP-4426677-A1 BIS(HETERO)ARYL THIOETHER (THIO)AMIDES AS FUNGICIDAL COMPOUNDS Bayer Aktiengesellschaft (DE) 2024-09-11 EP claimed
CN-118541353-A Bis (hetero) aryl thioether (thio) amides as fungicidal compounds 拜耳公司 2024-08-23 CN claimed
WO-2023078915-A1 BIS(HETERO)ARYL THIOETHER (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2023-05-11 WO claimed
US-20250064060-A1 BIS(HETERO)ARYL THIOETHER (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2025-02-27 US disclosed
US-20250042886-A1 BIS(HETERO)ARYL THIOETHER OXADIAZINES AS FUNGICIDAL COMPOUNDS BAYER S.A.S. (FR) 2025-02-06 US disclosed
EP-4441049-A1 BIS(HETERO)ARYL THIOETHER OXADIAZINES AS FUNGICIDAL COMPOUNDS Bayer Aktiengesellschaft (DE) 2024-10-09 EP disclosed
EP-4426677-A1 BIS(HETERO)ARYL THIOETHER (THIO)AMIDES AS FUNGICIDAL COMPOUNDS Bayer Aktiengesellschaft (DE) 2024-09-11 EP disclosed
CN-118541353-A Bis (hetero) aryl thioether (thio) amides as fungicidal compounds 拜耳公司 2024-08-23 CN disclosed
CN-118317956-A Bis (hetero) aryl thioether oxadiazines as fungicidal compounds 拜耳公司 2024-07-09 CN disclosed
WO-2023099445-A1 BIS(HETERO)ARYL THIOETHER OXADIAZINES AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2023-06-08 WO disclosed
WO-2023078915-A1 BIS(HETERO)ARYL THIOETHER (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2023-05-11 WO disclosed
US-20220023311-A1 HEPATITIS B CORE PROTEIN MODULATORS ASSEMBLY BIOSCIENCES INC (US) 2022-01-27 US disclosed
US-20220023311-A1 HEPATITIS B CORE PROTEIN MODULATORS ASSEMBLY BIOSCIENCES INC (US) 2022-01-27 US disclosed
US-10987360-B2 Hepatitis B core protein modulators ASSEMBLY BIOSCIENCES, INC. (US) 2021-04-27 US disclosed
US-10987360-B2 Hepatitis B core protein modulators ASSEMBLY BIOSCIENCES, INC. (US) 2021-04-27 US disclosed
US-20190255067-A1 HEPATITIS B CORE PROTEIN MODULATORS ASSEMBLY BIOSCIENCES INC (US) 2019-08-22 US disclosed
US-20190255067-A1 HEPATITIS B CORE PROTEIN MODULATORS ASSEMBLY BIOSCIENCES INC (US) 2019-08-22 US disclosed
EP-3512845-A1 HEPATITIS B CORE PROTEIN MODULATORS Assembly Biosciences, Inc. (US) 2019-07-24 EP disclosed
WO-2018053157-A1 HEPATITIS B CORE PROTEIN MODULATORS ASSEMBLY BIOSCIENCES, INC. (US) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042886-A1 BIS(HETERO)ARYL THIOETHER OXADIAZINES AS FUNGICIDAL COMPOUNDS CYP4Z1, STS, HPD MAPT 2106/4885LMNA 4792/4885PDE7A 3482/4885
US-10987360-B2 Hepatitis B core protein modulators HAVCR2, FABP1, MAVS MAPT 3090/4885LMNA 4700/4885PDE7A 3206/4885
US-20190255067-A1 HEPATITIS B CORE PROTEIN MODULATORS HAVCR2, FABP1, MAVS MAPT 3090/4885LMNA 4700/4885PDE7A 3206/4885
US-20250064060-A1 BIS(HETERO)ARYL THIOETHER (THIO)AMIDES AS FUNGICIDAL COMPOUNDS TST, TPMT, NAT1 MAPT 1162/4885LMNA 4788/4885PDE7A 3827/4885
US-20220023311-A1 HEPATITIS B CORE PROTEIN MODULATORS HAVCR2, FABP1, MAVS MAPT 3090/4885LMNA 4700/4885PDE7A 3206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.