Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21176216 | 0.78 | KMT2A (0.42) | HPGDGAAKDM4ENPSR1ALDH1A1 | |
| SCHEMBL21176280 | 0.78 | KMT2A (0.49) | HPGDGAAKDM4ENPSR1ALDH1A1 | |
| SCHEMBL7100866 | 0.76 | HPGD (0.48) | HPGDGAAKDM4ENPSR1ALDH1A1 | |
| SCHEMBL11550667 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL28288363 | 0.69 | CHRNB2 (0.39) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL7815263 | 0.69 | ALDH1A1 (0.40) | KDM4ENPSR1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10786707 | 0.69 | ALDH1A1 (0.40) | KDM4ENPSR1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL31016233 | 0.68 | KMT2A (0.50) | GAANPSR1KMT2AMAPTMEN1 | |
| SCHEMBL6743611 | 0.68 | ALDH1A1 (0.38) | KDM4ENPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL27183337 | 0.68 | LTA4H (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512836-A1 | ANTIVIRAL COMPOUNDS | Haplogen GmbH (AT) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |