Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.39 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.39 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.39 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.39 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098472 | 0.79 | HPGD (0.53) | HPGDALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7098463 | 0.77 | ALDH1A1 (0.40) | HPGDALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7100804 | 0.77 | HPGD (0.40) | HPGDALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5268183 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL27744904 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL27530431 | 0.76 | CTSB (0.44) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL19975099 | 0.76 | HPGD (0.46) | HPGDALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28010685 | 0.74 | POLB (0.43) | HPGDALDH1A1KMT2AMEN1BCHE | |
| SCHEMBL11051963 | 0.74 | MAOB (0.48) | ALDH1A1KDM4E | |
| SCHEMBL16166282 | 0.73 | SLC1A3 (0.41) | HPGDALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |