3-Hydroxybutyric Acid, (+/-)-

3-Hydroxybutyric Acid, (+/-)-

SCHEMBL19976113

CC(O)CC(=O)O.CC(O)CC(=O)O.CC(O)CC(=O)OCC(O)CO

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.47
DGKA P23743 1/20 0.41
PRKCA P17252 4/20 0.40
FAAH O00519 2/20 0.39
SLC22A6 Q4U2R8 1/20 0.37
MAPT P10636 1/20 0.35
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Hydroxybutyric Acid, (+/-)- SCHEMBL22300929 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL15319570 0.93 KDM4E (0.53) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL2552726 0.93 KDM4E (0.53) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL28603990 0.86 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL25476040 0.86 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL21471824 0.83 PRKCA (0.45) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL21471879 0.83 PRKCA (0.45) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL8954153 0.81 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL4805747 0.81 KDM4E (0.53) KDM4EDUSP3MEN1KMT2ALMNA
3-Hydroxybutyric Acid, (+/-)- SCHEMBL20524888 0.80 SLC22A6 (0.50) LMNASLC22A6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10736867-B2 Glyceryl 3-hydroxybutyrates for traumatic brain injury NEUROENERGY VENTURES, INC. (US) 2020-08-11 US claimed
US-20180177753-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR MIGRAINE SYMPTOM MANAGEMENT NEUROENERGY VENTURES, INC. (US) 2018-06-28 US claimed
US-11638702-B2 Glyceryl 3-hydroxybutyrates for traumatic brain injury NeuroEnerygy Ventures, Inc. (US) 2023-05-02 US disclosed
US-20200297686-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR TRAUMATIC BRAIN INJURY NeuroEnerygy Ventures, Inc. (US) 2020-09-24 US disclosed
US-10736867-B2 Glyceryl 3-hydroxybutyrates for traumatic brain injury NEUROENERGY VENTURES, INC. (US) 2020-08-11 US disclosed
EP-3568129-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR TRAUMATIC BRAIN INJURY Neuroenergy Ventures, Inc. (US) 2019-11-20 EP disclosed
WO-2018132189-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR TRAUMATIC BRAIN INJURY NEUROENERGY VENTURES, INC. (US) 2018-07-19 WO disclosed
US-20180193300-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR TRAUMATIC BRAIN INJURY NEUROENERGY VENTURES, INC. (US) 2018-07-12 US disclosed
US-9925164-B1 Glyceryl 3-hydroxybutyrates for traumatic brain injury NEUROENERGY VENTURES, INC. (US) 2018-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200297686-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR TRAUMATIC BRAIN INJURY FABP7, B3GAT3, PYGB KDM4E 3535/4885DUSP3 4584/4885MEN1 3920/4885
US-20180177753-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR MIGRAINE SYMPTOM MANAGEMENT HTR3B, MGLL, HTR3A KDM4E 2988/4885DUSP3 3128/4885MEN1 1094/4885
US-10736867-B2 Glyceryl 3-hydroxybutyrates for traumatic brain injury FABP7, B3GAT3, PYGB KDM4E 3535/4885DUSP3 4584/4885MEN1 3920/4885
US-20180193300-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR TRAUMATIC BRAIN INJURY FABP7, B3GAT3, PYGB KDM4E 3535/4885DUSP3 4584/4885MEN1 3920/4885
US-11638702-B2 Glyceryl 3-hydroxybutyrates for traumatic brain injury FABP7, B3GAT3, PYGB KDM4E 3535/4885DUSP3 4584/4885MEN1 3920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.