Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16965201 | 0.79 | MAPK14 (0.57) | MLYCDHDAC6 | |
| SCHEMBL19976443 | 0.77 | HDAC4 (0.44) | MLYCDHDAC4HDAC6HDAC1HDAC3 | |
| SCHEMBL16965137 | 0.76 | LMNA (0.53) | MLYCDHDAC4HDAC6HDAC1HDAC3 | |
| SCHEMBL18358995 | 0.75 | MLYCD (0.44) | MLYCDHDAC4HDAC6HDAC1HDAC3 | |
| SCHEMBL19976449 | 0.75 | HDAC4 (0.48) | MLYCDHDAC4HDAC6HDAC1HDAC3 | |
| SCHEMBL16964307 | 0.75 | PSMB8 (0.46) | MLYCDHDAC4HDAC6HDAC1HDAC3 | |
| SCHEMBL16964231 | 0.73 | MLYCD (0.55) | MLYCDHDAC3 | |
| SCHEMBL16964549 | 0.72 | NPC1 (0.47) | MLYCDHDAC4HDAC6HDAC1HDAC3 | |
| SCHEMBL16964203 | 0.71 | MLYCD (0.54) | MLYCDTSHRHDAC3 | |
| SCHEMBL16964303 | 0.71 | MLYCD (0.58) | MLYCDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | disclosed |