Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 15/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358995 | 0.79 | MLYCD (0.44) | HDAC4HDAC6HDAC1MLYCDHDAC2 | |
| SCHEMBL16964102 | 0.77 | PLK1 (0.61) | HDAC4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL19976499 | 0.75 | MLYCD (0.46) | HDAC4HDAC6HDAC1MLYCDHDAC3 | |
| SCHEMBL19976443 | 0.75 | HDAC4 (0.44) | HDAC4HDAC6HDAC1MLYCDHDAC2 | |
| SCHEMBL18359000 | 0.74 | MLYCD (0.42) | HDAC4HDAC6HDAC1MLYCDHDAC3 | |
| SCHEMBL16965137 | 0.74 | LMNA (0.53) | HDAC4HDAC6HDAC1MLYCDHDAC2 | |
| SCHEMBL24386337 | 0.74 | CES1 (0.44) | HDAC4HDAC6HDAC1MLYCD | |
| SCHEMBL16964231 | 0.74 | MLYCD (0.55) | MLYCDHDAC3 | |
| SCHEMBL18358989 | 0.73 | MLYCD (0.44) | HDAC4HDAC6HDAC1MLYCDHDAC3 | |
| SCHEMBL16964206 | 0.73 | KDM4E (0.43) | HDAC4HDAC6HDAC1MLYCDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | disclosed |