Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 16/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001177 | 0.93 | ALOX5AP (0.43) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL2007615 | 0.93 | ALOX5AP (0.44) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL2006586 | 0.93 | ALOX5AP (0.39) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL2006720 | 0.92 | ALOX5AP (0.44) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL2003925 | 0.90 | ALOX5 (0.39) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL2005424 | 0.90 | ALOX5AP (0.42) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL2003159 | 0.89 | ALOX5AP (0.46) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL2007666 | 0.89 | MAPK1 (0.43) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL2010313 | 0.89 | FAAH (0.42) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL2002225 | 0.88 | ALOX5AP (0.39) | ALOX5APALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960544-B2 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-06-14 | — | — | US | disclosed |