Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976784 | 0.90 | MAPK1 (0.38) | POLBMAPK1DGAT2NAMPT | |
| SCHEMBL19976739 | 0.89 | HPGD (0.37) | POLBHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL19976851 | 0.88 | POLB (0.35) | POLBHPGDKMT2AMAPK1LMNA | |
| SCHEMBL19976944 | 0.88 | MAPK1 (0.36) | POLBHPGDKMT2AMAPK1LMNA | |
| SCHEMBL19976880 | 0.87 | PDE10A (0.36) | POLBHPGDMAPK1LMNANAMPT | |
| SCHEMBL19976740 | 0.86 | HPGD (0.39) | POLBHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL19976737 | 0.86 | HPGD (0.35) | POLBHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL19976909 | 0.84 | POLB (0.34) | POLBHPGDMAPK1LMNANAMPT | |
| SCHEMBL19976759 | 0.82 | LMNA (0.36) | POLBHPGDMAPK1LMNADGAT2 | |
| SCHEMBL19976803 | 0.82 | MAPK1 (0.38) | POLBHPGDMAPK1LMNADGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |