Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 4/20 | 0.73 |
| ▸ | EIF4H | Q15056 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976939 | 0.88 | ALDH1A1 (0.56) | PABPC1EIF4HMEN1KMT2AALDH1A1 | |
| SCHEMBL19976908 | 0.87 | ALDH1A1 (0.55) | PABPC1EIF4HMEN1KMT2AALDH1A1 | |
| SCHEMBL19976894 | 0.84 | ALDH1A1 (0.62) | PABPC1EIF4HMEN1KMT2AALDH1A1 | |
| SCHEMBL16999319 | 0.83 | PABPC1 (0.66) | PABPC1EIF4HMEN1KMT2AALDH1A1 | |
| SCHEMBL16993979 | 0.83 | PABPC1 (0.66) | PABPC1EIF4HMEN1KMT2AALDH1A1 | |
| SCHEMBL19977127 | 0.80 | TRPV1 (0.54) | MEN1KMT2ALMNAHTT | |
| SCHEMBL19976946 | 0.78 | ALDH1A1 (0.65) | PABPC1EIF4HMEN1KMT2AALDH1A1 | |
| SCHEMBL19976910 | 0.78 | PGR (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL12864492 | 0.77 | MEN1 (0.70) | PABPC1EIF4HMEN1KMT2AALDH1A1 | |
| SCHEMBL19977030 | 0.75 | MAPT (0.57) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |