Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977089 | 0.98 | L3MBTL1 (0.52) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6054998 | 0.83 | L3MBTL1 (0.76) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL19976947 | 0.81 | MEN1 (0.53) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28987534 | 0.80 | L3MBTL1 (0.72) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL12308333 | 0.80 | ALDH1A1 (0.62) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16993990 | 0.79 | USP30 (0.56) | L3MBTL1KDM4EKMT2APOLBHDAC6 | |
| SCHEMBL19976922 | 0.79 | HPGD (0.66) | KDM4EALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL19976955 | 0.78 | POLB (0.53) | ALDH1A1LMNAPOLBTSHRSMN1; SMN2 | |
| SCHEMBL16994026 | 0.78 | USP30 (0.55) | L3MBTL1KDM4EKMT2APOLBHDAC6 | |
| SCHEMBL6719072 | 0.75 | KDM4E (0.51) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |