Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976922 | 0.90 | HPGD (0.66) | POLBHPGDHTTNPC1RAB9A | |
| SCHEMBL19977072 | 0.86 | LMNA (0.54) | POLBHPGDHTTLMNASMN1; SMN2 | |
| SCHEMBL19977018 | 0.86 | SMN1; SMN2 (0.50) | POLBHPGDNPC1RAB9ALMNA | |
| SCHEMBL19977070 | 0.85 | KCNK3 (0.48) | POLBHPGDRAB9ALMNAALDH1A1 | |
| SCHEMBL19977071 | 0.84 | LMNA (0.45) | POLBHPGDHTTNPC1RAB9A | |
| SCHEMBL19976970 | 0.84 | NPC1 (0.53) | HPGDHTTNPC1RAB9ALMNA | |
| SCHEMBL19976979 | 0.83 | TAS2R14 (0.50) | POLBLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19977134 | 0.83 | HDAC1 (0.46) | POLBHPGDHTTNPC1RAB9A | |
| SCHEMBL19976957 | 0.82 | PGR (0.44) | POLBHPGDHTTRAB9ALMNA | |
| SCHEMBL11769542 | 0.82 | POLB (0.77) | POLBHPGDHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |